I have a Verizon Fios business account at my home. I'm using a G3100 router. I haven't been able to configure email clients like Microsoft Outlook or Mozilla Thunderbird to traverse the router and reach a mail server named "example.net" (for example) that I have on my home network to retrieve email using secure POP3 on port 995. When I use Outlook from a computer on my home network and bypass the router and connect to the mail server using the private address on my home network, everything works just fine.
I can telnet to the mail server on port 995 from another server on a different network, confirming that port forwarding is properly configured. When I try to connect through the router using Outlook and Thunderbird, I see no connection attempts on the mail server.
It looks like Outlook and Thunderbird are doing something that's being blocked by the router. Does anyone have any thoughts on what's happening?